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Sunday sees the first Wear-Tyne derby since 2024, but who will emerge victorious – the Black Cats or Newcastle?
"For most of last season, no one would have predicted Sunderland rising to the top flight and holding their own with Eddie Howe's Newcastle, much less being above them in the table," stated football expert Chris Sutton.
"The situation is very different now, and the way Sunderland play convinces me they've got a real chance."
He is offering scoreline guesses for all 380 Premier League games this season, in competition with artificial intelligence, the public and a variety of guests.
For week 16, he faces off against England Gaming star Daniel 'Stingray' Ray.
Ray is competing for honours for the eLions – the Football Association's formal esports team – at the football simulation Uefa eEuro 2025 finals tournament, which will occur at Twickenham Stadium on Saturday.
You can watch Uefa's video platform, IG Live and short-form video channels, as well as EA Sports FC Twitch and YouTube and the national team's Twitch.
What are your thoughts with their forecasts? Share your own guesses below.
The most commonly selected scoreline picked for each game is displayed on the scoreboards at the bottom of this page.
Predicting the right outcome (selecting a win, draw or defeat) is worth ten points. A perfect prediction earns 40 points.
Ray, who represents his club side and the Premier League champions as well as England, is making his debut at the eEuros finals after passing the qualifying.
Eight players will represent their nations at the finals in a knockout format, competing for a six-figure prize fund and a prestigious spot in the world finals play-offs, with Denmark's Anders Vejrgang looking to retain the title he won last year.
"I'm feeling really good for it," Ray stated. "I have a really good coach with me and practice has been going well.
"It's always an honour to play for your country. Obviously when you are younger, you fantasise about doing it as an actual footballer, but when you pursue a career in this field and there is an opportunity to represent England, donning the national jersey is something special.
"I beat Vejrgang 9-4 in qualifying to get here. I've played against him over the course of the season just in practice, and in other tournaments before - but I'd never beaten him in a tournament before.
"I believe he is the best player in the world so defeating him in a tournament like this just provides a huge surge of confidence."
Premier League Weekend Preview
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The London club were impressive against the Gunners at the end of November, when they secured a point after being reduced to 10 men, and I was thinking this is it, they could potentially be title contenders.
In the matches following, however, they were beaten physically by Leeds, looked flat against Bournemouth and this week got turned over by Atalanta in the Champions League.
So head coach Enzo Maresca desperately requires a win here to restore momentum, but it is a tough ask because the Merseyside club are such a potent team.
Two of their stars are playing at the top of their game and Everton have got a bit of form at the moment.
Current evidence suggests you would likely back the visitors, while the most prudent prediction would probably be a draw, but I'm going against logic.
Chelsea haven't given me any compelling evidence to back them recently, but I just have a feeling Chelsea will take this one because they are at home and they are in need of three points.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'll be at this game and it will be intriguing to see what we get from the Reds.
It was great to see for Reds boss Arne Slot to get such a great win at Inter Milan on Tuesday following all the controversy with Mohamed Salah this week.
Slot ought not to put up with that nonsense. I know Salah has been a legend for Liverpool but essentially Slot just wants to win games and there is nothing personal in his team selection.
Liverpool changed their tactical setup against Inter and went with a midfield diamond and two up top.
The media is going to be talking about whether Salah is included for this game, but the only way he is going to be reintegrated is if he apologises.
Slot's attention will be on winning this game, but it is a tough one.
You could argue it is the same for most teams but I find Brighton so mercurial. I always feel they have got a goal in them, but they are defensively susceptible too.
Liverpool need to get back to stringing wins together, but I am not sure how much their energy spent at the San Siro will have taken out of them.
I have whacked a couple of Brighton players in my FPL team, so they will probably lose now - but I do think they can get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
Sunderland have had the week off while Newcastle had to exert themselves against Bayer Leverkusen on Wednesday, only to let their lead slip away late on.
With the exception of their excellent performance against Everton a couple of weeks ago, Newcastle's away form hasn't been great, especially straight after they've played in the Champions League.
The pattern suggests that trend to continue on Sunday, and their lack of freshness is likely to be a key element in how this game goes because of their rivals' high press.
Their match against Arsenal demonstrated how incessant Regis le Bris's side are. They overpowered the Gunners, and it was a joy to watch.
Commentators talks about how Granit Xhaka has been brilliant for the Black Cats, and he has been brilliant, but Noah Sadiki, who plays alongside him, has also been one of the top transfers and warrants praise too.
This promises to be this being the best game|most exciting fixture